Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Chromosomal instability, microsatellite instability and CpG island methylator phenotype: roles in small intestinal carcinogenesis].

Der Pathologe - 1 Nov 2011

Bläker H, Warth A, Kloor M, Schirmacher P

Abstract excerpt

AIMS: Intestinal carcinogenesis is associated with genetic instability affecting either the chromosomal level (CIN) or microsatellite DNA sequences (MIN). In addition, epigenetic alterations, such as aberrant CpG island methylation (CIMP) may contribute to tumor development. While these single genetic alterations have frequently been addressed in intestinal carcinogenesis little is known about the interaction of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CpG Islands

Share to BRAF gene

Share to KRAS gene

Share to Intestinal Neoplasms

Share to Microsatellite Instability

Share to Phenotype

Source

Identifiers

PMID: 21915661
DOI: 10.1007/s00292-011-1509-0

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Chromosomal instability, microsatellite instability and CpG island methylator phenotype: roles in small intestinal carcinogenesis].PMID 21915661Read ↗

Genetics and epigenetics of small bowel adenocarcinoma: the interactions of CIN, MSI, and CIMP.Semantic proximity Read ↗

Molecular pathways in colorectal cancerSemantic proximity Read ↗

Four molecular subtypes of colorectal cancer and their precursor lesions.Semantic proximity Read ↗

Pathways of colorectal carcinogenesis.Semantic proximity Read ↗

Microsatellite instability in colorectal cancerSemantic proximity Read ↗

Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability.Semantic proximity Read ↗

Genetics, cytogenetics, and epigenetics of colorectal cancer.Semantic proximity Read ↗

Actionable Molecular Pathways in Colorectal CancerSemantic proximity Read ↗

CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer.Semantic proximity Read ↗

Characterization of Chilean patients with sporadic colorectal cancer according to the three main carcinogenic pathways: Microsatellite instability, CpG island methylator phenotype and Chromosomal instability.Semantic proximity Read ↗

The methylator phenotype in microsatellite stable colorectal cancers is characterized by a distinct gene expression profile.Semantic proximity Read ↗

A novel classification of colorectal tumors based on microsatellite instability, the CpG island methylator phenotype and chromosomal instability: implications for prognosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.