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Article

Four molecular subtypes of colorectal cancer and their precursor lesions.

Archives of pathology & laboratory medicine - 1 Jun 2011

Kang Gyeong Hoon

Abstract excerpt

CONTEXT: In addition to chromosomal instability and microsatellite instability (MSI), a third pathway, epigenetic instability, has been implicated in progression to colorectal carcinogenesis. CpG island methylator phenotype (CIMP) refers to a subset of colorectal cancers (CRCs) that occur through the epigenetic instability pathway and that are characterized by widespread hypermethylation of promoter CpG island...

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PMID: 21631262
DOI: 10.5858/2010-0523-RA.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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