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Actionable Molecular Pathways in Colorectal Cancer

2024-10-30

Abstract excerpt

Colorectal cancer (CRC) arises through a combination of genetic and epigenetic alterations that affect key pathways involved in tumor growth and progression. This review examines the major molecular pathways driving CRC, including Chromosomal Instability (CIN), Microsatellite Instability (MSI), and the CpG Island Methylator Phenotype (CIMP). Key mutations in genes such as APC, KRAS, NRAS, BRAF, and TP53 activate s...

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Identifiers and source

Literature Corpus work
e19ac75c-930c-532f-8fb3-2b2c63022fc0
DOI
10.20944/preprints202410.2231.v1
Open publication

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Actionable Molecular Pathways in Colorectal CancerDOI 10.20944/preprints202410.2231.v1
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