Association of interleukin-28B and hepatitis C genotype 1 with a high viral load and response to pegylated interferon plus ribavirin therapy.

doi:10.1159/000333215

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Article

Association of interleukin-28B and hepatitis C genotype 1 with a high viral load and response to pegylated interferon plus ribavirin therapy.

Digestion - 1 Jan 2011

Takita Masahiro, Hagiwara Satoru, Arizumi Tadaaki, Hayaishi Sousuke, Ueda Taisuke, Kitai Satoshi, Yada Norihisa, Inoue Tatsuo, Minami Yasunori, Chung Hobyung, Ueshima Kazuomi, Sakurai Toshiharu, Kudo Masatoshi

Abstract excerpt

BACKGROUND: Pegylated interferon (PEG-IFN) plus ribavirin therapy is the current standard treatment for chronic hepatitis C (CHC) genotype 1 with high viral load. A common genetic variation near the IL28B gene has been found to affect the response to PEG-IFN plus ribavirin therapy for CHC. The aims of this study were to analyze the association between the rs8099917 genotype and treatment response in a cohort...

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PMID: 22156487
DOI: 10.1159/000333215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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