Clinical utility of host genetic IL-28B variants in hepatitis C virus genotype 1 Asian patients retreated with pegylated interferon plus ribavirin.

doi:10.1111/jgh.12211

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Article

Clinical utility of host genetic IL-28B variants in hepatitis C virus genotype 1 Asian patients retreated with pegylated interferon plus ribavirin.

Journal of gastroenterology and hepatology - 1 Sept 2013

Huang Chung-Feng, Yeh Ming-Lun, Hsieh Meng-Hsuan, Hsieh Ming-Yen, Lin Zu-Yau, Chen Shinn-Cherng, Wang Liang-Yen, Huang Jee-Fu, Juo Suh-Hang Hank, Lin Yi-Ching, Dai Chia-Yen, Chuang Wan-Long, Yu Ming-Lung

Abstract excerpt

BACKGROUND AND AIM: Host interleukin-28B (IL-28B) genetic variants determine a sustained virological response (SVR) in hepatitis C virus genotype 1 (HCV-1) treatment-naïve patients. Its impact on treatment-experienced Asian patients with peginterferon/ribavirin in is to be elucidated. METHODS: IL-28B rs8099917 genotype was determined in 70 HCV-1 treatment-experienced patients retreated with 48-week...

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PMID: 23560893
DOI: 10.1111/jgh.12211

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