Article
Assessment of interleukin 28B genotype as a predictor of response to combined therapy with pegylated interferon plus ribavirin in HCV infected Egyptian patients.
Cytokine - 1 Aug 2015
Fathy Mona M, Abo Taleb Mohamed E, El Hawary Mohamed S, Nabih Mona I, Aref Wael M, Makhlouf Manal M
Abstract excerpt
BACKGROUND AND AIM: Single nucleotide polymorphisms (SNPs) of interleukin 28B (IL28B) gene is associated with spontaneous clearance and variable response to combined therapy with pegylated interferon (PEG-IFN) and ribavirin (RBV) in chronic hepatitis C virus (HCV) infected patients. This study aimed at assessing the value of IL28B rs8099917 gene polymorphism in predicting sustained virological response (SVR)...
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