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Article

High altitude adaptation in Daghestani populations from the Caucasus.

Human genetics - 1 Mar 2012

Pagani Luca, Ayub Qasim, MacArthur Daniel G, Xue Yali, Baillie J Kenneth, Chen Yuan, Kozarewa Iwanka, Turner Daniel J, Tofanelli Sergio, Bulayeva Kazima, Kidd Kenneth, Paoli Giorgio, Tyler-Smith Chris

Abstract excerpt

We have surveyed 15 high-altitude adaptation candidate genes for signals of positive selection in North Caucasian highlanders using targeted re-sequencing. A total of 49 unrelated Daghestani from three ethnic groups (Avars, Kubachians, and Laks) living in ancient villages located at around 2,000 m above sea level were chosen as the study population. Caucasian (Adygei living at sea level, N = 20) and CEU (CEPH...

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Source

Open in PubMed Open full text

Identifiers

PMID: 21904933
DOI: 10.1007/s00439-011-1084-8
PMCID: PMC3312735

Genes

EGLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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