Article
Dynamics of gag-pol minority viral populations in naive HIV-1-infected patients failing protease inhibitor regimen.
AIDS (London, England) - 13 Nov 2011
Larrouy Lucile, Charpentier Charlotte, Landman Roland, Capitant Catherine, Chazallon Corine, Yeni Patrick, Peytavin Gilles, Damond Florence, Brun-Vezinet Françoise, Descamps Diane
Abstract excerpt
OBJECTIVE: Recently, we have reported the role of baseline gag cleavage site mutations on the virological outcome of a dual-boosted protease inhibitor regimen in antiretroviral-naive patients (2IP-ANRS 127 trial). The objective of this substudy was to characterize, in patients experiencing virological failure, from the 2IP-ANRS 127 trial, the viral quasispecies present at baseline and at virological failure in...
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