Article
Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors.
Journal of virology - 1 Jun 1996
Doyon L, Croteau G, Thibeault D, Poulin F, Pilote L, Lamarre D
Abstract excerpt
Protease inhibitors are potent antiviral agents against human immunodeficiency virus type 1. As with reverse transcriptase inhibitors, however, resistance to protease inhibitors can develop and is attributed to the appearance of mutations in the protease gene. With the substrate analog protease i...
Topics
- Amino Acid Sequence
- Antiviral Agents
- Base Sequence
- Drug Resistance
- Gene Products, gag
- HIV Protease
- HIV Protease Inhibitors
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation