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Article

Variability at human immunodeficiency virus type 1 subtype C protease cleavage sites: an indication of viral fitness?

Journal of virology - 1 Sept 2003

de Oliveira Tulio, Engelbrecht Susan, Janse van Rensburg Estrelita, Gordon Michelle, Bishop Karen, zur Megede Jan, Barnett Susan W, Cassol Sharon

Abstract excerpt

Naturally occurring polymorphisms in the protease of human immunodeficiency virus type 1 (HIV-1) subtype C would be expected to lead to adaptive (compensatory) changes in protease cleavage sites. To test this hypothesis, we examined the prevalences and patterns of cleavage site polymorphisms in t...

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Identifiers

PMID: 12915557
DOI: 10.1128/jvi.77.17.9422-9430.2003
PMCID: PMC187406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12915557-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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