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Article

Effect of heme oxygenase-1 polymorphisms on lung function and gene expression.

BMC medical genetics - 8 Sept 2011

Tanaka Goh, Aminuddin Farzian, Akhabir Loubna, He Jian-Qing, Shumansky Karey, Connett John E, Anthonisen Nicholas R, Abboud Raja T, Paré Peter D, Sandford Andrew J

Abstract excerpt

BACKGROUND: Oxidative stress induced by smoking is considered to be important in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Heme oxygenase-1 (HMOX1) is an essential enzyme in heme catabolism that is induced by oxidative stress and may play a protective role as an antioxidant in the lung. We determined whether HMOX1 polymorphisms were associated with lung function in COPD patients and...

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Source

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Identifiers

PMID: 21902835
DOI: 10.1186/1471-2350-12-117
PMCID: PMC3180266

Genes

HMOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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