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Article

Ozone exposure, antioxidant genes, and lung function in an elderly cohort: VA normative aging study.

Occupational and environmental medicine - 1 Nov 2008

Alexeeff S E, Litonjua A A, Wright R O, Baccarelli A, Suh H, Sparrow D, Vokonas P S, Schwartz J

Abstract excerpt

BACKGROUND: Ozone (O3) exposure is known to cause oxidative stress. This study investigated the acute effects of O(3) on lung function in the elderly, a suspected risk group. It then investigated whether genetic polymorphisms of antioxidant genes (heme oxygenase-1 (HMOX1) and glutathione S-transferase pi (GSTP1)) modified these associations. METHODS: 1100 elderly men from the Normative Aging Study were examined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18524839
DOI: 10.1136/oem.2007.035253
PMCID: PMC2575239

Genes

GSTP1
HMOX1
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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