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Article

C868T single nucleotide polymorphism and HIV type 1 disease progression among postpartum women in Kenya.

AIDS research and human retroviruses - 1 Jun 2012

Choi Robert Y, Fowke Keith R, Juno Jennifer, Lohman-Payne Barbara, Oyugi Julius O, Brown Elizabeth R, Bosire Rose, John-Stewart Grace, Farquhar Carey

Abstract excerpt

The C868T single nucleotide polymorphism in the CD4 receptor encodes an amino acid substitution of tryptophan for arginine in the third domain. Previous studies suggest that C868T increases the risk of HIV-1 acquisition; however, the influence of this single nucleotide polymorphism (SNP) on disease progression has not been established. The presence of the C868T polymorphism was not statistically significantly...

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Identifiers

PMID: 21902583
DOI: 10.1089/AID.2011.0095
PMCID: PMC3358105

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