Article
HLA-G 14 bp deletion/insertion polymorphism and mother-to-child transmission of HIV.
Tissue antigens - 1 Mar 2014
Segat L, Zupin L, Kim H-Y, Catamo E, Thea D M, Kankasa C, Aldrovandi G M, Kuhn L, Crovella S
Abstract excerpt
The human leukocyte antigen HLA-G, highly expressed at the maternal-fetal interface, has a pivotal role in mediating immune tolerance. In this study we investigated the influence of HLA-G 14 bp insertion polymorphism in human immunodeficiency virus (HIV)-1 mother-to-child HIV-1 transmission. The 14 bp insertion polymorphism was analyzed among 99 HIV-1 positive mothers and 329 infants born to HIV-positive mothers...
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