Article
The CD4 C868T Polymorphism and Its Correlation with HIV-1 Infection in a Chinese Population.
AIDS research and human retroviruses - 1 May 2015
Lu Yu, Wu Junrong, Qin Xue, Xie Li, Ma Liping, Huang Xiuli, Zhao Jiangyang, Liu Yanqiong, Chen Xuejie, Li Shan
Abstract excerpt
Previous studies performed in Kenya have suggested that the C868T single nucleotide polymorphism (SNP) in CD4 increases the risk of HIV-1 acquisition; however, no relevant study has been conducted in China. To evaluate the influence of this SNP on risk of HIV-1 infection in a Chinese population, the CD4 genotype was determined by DNA sequencing in 101 HIV-1 patients and 102 healthy controls. No significant...
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