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Article

Comparison of HIV-1 nef and gag Variations and Host HLA Characteristics as Determinants of Disease Progression among HIV-1 Vertically Infected Kenyan Children.

PloS one - 1 Jan 2015

Saina Matilda Chelimo, Bi Xiuqiong, Lihana Raphael, Lwembe Raphael, Ishizaki Azumi, Panikulam Annie, Palakudy Tresa, Musoke Rachel, Owens Mary, Songok Elijah Maritim, Ichimura Hiroshi

Abstract excerpt

OBJECTIVES: Disease progression varies among HIV-1-infected individuals. The present study aimed to explore possible viral and host factors affecting disease progression in HIV-1-infected children. METHODS: Since 2000, 102 HIV-1 vertically-infected children have been followed-up in Kenya. Here we studied 29 children (15 male/14 female) who started antiretroviral treatment at <5 years of age (rapid progressors;...

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Identifiers

PMID: 26317223
DOI: 10.1371/journal.pone.0137140
PMCID: PMC4552823

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