Article
IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients.
World journal of gastroenterology - 28 Sept 2014
Rosso Chiara, Abate Maria Lorena, Ciancio Alessia, Strona Silvia, Caviglia Gian Paolo, Olivero Antonella, Touscoz Giovanni Antonio, Rizzetto Mario, Pellicano Rinaldo, Smedile Antonina
Abstract excerpt
AIM: To clarify the association of interleukin-28B (IL28B) single nucleotide polymorphisms (SNPs) with hepatitis C virus (HCV) viremia changes for assessment of interferon (IFN) response. METHODS: A cohort of 118 Caucasian treatment-naïve HCV-G1 infected patients, treated with pegylated-IFN alpha 2a or 2b associated with ribavirin (53 responders, 65 non-responders) during the period 2010-2012, were genotyped for...
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