Article
Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression.
Hepatology (Baltimore, Md.) - 1 Jan 2012
Jiao Jingjing, Sastre David, Fiel Maria Isabel, Lee Ursula E, Ghiassi-Nejad Zahra, Ginhoux Florent, Vivier Eric, Friedman Scott L, Merad Miriam, Aloman Costica
Abstract excerpt
UNLABELLED: Although hepatic fibrosis typically follows chronic inflammation, fibrosis will often regress after cessation of liver injury. In this study, we examined whether liver dendritic cells (DCs) play a role in liver fibrosis regression using carbon tetrachloride to induce liver injury. We examined DC dynamics during fibrosis regression and their capacity to modulate liver fibrosis regression upon cessation...
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