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Article

Deactivation of hepatic stellate cells during liver fibrosis resolution in mice.

Gastroenterology - 1 Oct 2012

Troeger Juliane S, Mederacke Ingmar, Gwak Geum-Youn, Dapito Dianne H, Mu Xueru, Hsu Christine C, Pradere Jean-Philippe, Friedman Richard A, Schwabe Robert F

Abstract excerpt

BACKGROUND & AIMS: Activated hepatic stellate cells (HSCs), the main fibrogenic cell type in the liver, undergo apoptosis after cessation of liver injury, which contributes to resolution of fibrosis. In this study, we investigated whether HSC deactivation constitutes an additional mechanism of liver fibrosis resolution. METHODS: HSC activation and deactivation were investigated by single-cell PCR and genetic...

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Identifiers

PMID: 22750464
DOI: 10.1053/j.gastro.2012.06.036
PMCID: PMC3848328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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