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Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX

30 Apr 2022

Abstract excerpt

The murine cell line GRX has been introduced as an experimental tool to study aspects of hepatic stellate cell biology. It was established from livers of C3H/HeN mice that were infected with cercariae of Schistosoma mansoni. Although these cells display a myofibroblast phenotype, they can accumulate intracellular lipids and acquire a fat-storing lipocyte phenotype when treated with retinol, insulin, and...

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PMID: 35563813
DOI: 10.3390/cells11091504

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