Phenotypical modulation of liver fat-storing cells by retinoids. Influence on unstimulated and growth factor-induced cell proliferation.

doi:10.1016/0168-8278(92)90160-q

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Article

Phenotypical modulation of liver fat-storing cells by retinoids. Influence on unstimulated and growth factor-induced cell proliferation.

Journal of hepatology - 1 Mar 1992

Pinzani M, Gentilini P, Abboud H E

Abstract excerpt

In conditions of chronic liver inflammation, liver fat-storing cells (FSC) differentiate into 'myofibroblast-like cells'. This transition is characterized by a gradual loss of vitamin A stores, and previous studies suggest a possible relationship between the intracellular retinoid content and the...

Topics

Analysis of Variance
Animals
Autoradiography
Cell Division
Cells, Cultured
DNA Replication
Diterpenes
Epidermal Growth Factor
Kinetics
Liver
Male
Phenotype
Platelet-Derived Growth Factor
Rats
Rats, Inbred Strains
Recombinant Proteins
Retinoids
Retinyl Esters

Source

Open in PubMed

Identifiers

PMID: 1500685
DOI: 10.1016/0168-8278(92)90160-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1500685-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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