Collagen synthesis in an established liver connective tissue cell line (GRX) during induction of the fat-storing phenotype.

doi:10.1016/0014-4800(92)90028-a

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Article

Collagen synthesis in an established liver connective tissue cell line (GRX) during induction of the fat-storing phenotype.

Experimental and molecular pathology - 1 Apr 1992

Pinheiro-Margis M, Margis R, Borojevic R

Abstract excerpt

We have studied collagen synthesis and secretion in an established liver connective tissue cell line (GRX) that can be induced in vitro to express either the myofibroblastic or the fat-storing (lipocyte) phenotype. In lipocytes, collagen synthesis was reduced. Their intracellular collagen degrada...

Topics

Animals
Cell Count
Cell Line
Collagen
Connective Tissue
Connective Tissue Cells
Fibroblasts
Lipid Metabolism
Liver
Liver Cirrhosis
Mice
Phenotype
Proline
Vitamin A

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