Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Collagen synthesis in an established liver connective tissue cell line (GRX) during induction of the fat-storing phenotype.

Experimental and molecular pathology - 1 Apr 1992

Pinheiro-Margis M, Margis R, Borojevic R

Abstract excerpt

We have studied collagen synthesis and secretion in an established liver connective tissue cell line (GRX) that can be induced in vitro to express either the myofibroblastic or the fat-storing (lipocyte) phenotype. In lipocytes, collagen synthesis was reduced. Their intracellular collagen degradation corresponded to 15% of newly synthesized collagen. In myofibroblasts, collagen synthesis was high but its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Cell Line
Share to Collagen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblasts

Share to Phenotype

Share to Proline

Source

Identifiers

PMID: 1587337
DOI: 10.1016/0014-4800(92)90028-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Collagen synthesis in an established liver connective tissue cell line (GRX) during induction of the fat-storing phenotype.PMID 1587337Read ↗

Neutral lipid synthesis and accumulation during in vitro induction of the lipocyte phenotype in hepatic connective tissue cells.Semantic proximity Read ↗

In vitro induction of the fat-storing phenotype in a liver connective tissue cell line-GRX.Semantic proximity Read ↗

Retinol uptake and metabolism, and cellular retinol binding protein expression in an in vitro model of hepatic stellate cells.Semantic proximity Read ↗

Phospholipid modifications during conversion of hepatic myofibroblasts into lipocytes (Ito-cells).Semantic proximity Read ↗

Instability of the myofibroblast phenotype in culture.Semantic proximity Read ↗

Induction of the lipocyte phenotype in murine hepatic stellate cells: reorganisation of the actin cytoskeleton.Semantic proximity Read ↗

Phenotypical modulation of liver fat-storing cells by retinoids. Influence on unstimulated and growth factor-induced cell proliferation.Semantic proximity Read ↗

Intermediate filaments modulation in an in vitro model of the hepatic stellate cell activation or conversion into the lipocyte phenotype.Semantic proximity Read ↗

Changes of sphingolipid species in the phenotype conversion from myofibroblasts to lipocytes in hepatic stellate cells.Semantic proximity Read ↗

Beta-carotene storage, conversion to retinoic acid, and induction of the lipocyte phenotype in hepatic stellate cells.Semantic proximity Read ↗

Variations of ganglioside biosynthetic pathways in the phenotype conversion from myofibroblasts to lipocytes in murine hepatic stellate cell line.Semantic proximity Read ↗

Ito-cell gene expression and collagen regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.