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Article

Rapid allele-specific PCR method for CDA 79A>C (K27Q) genotyping: a useful pharmacogenetic tool and world-wide polymorphism distribution.

Clinica chimica acta; international journal of clinical chemistry - 20 Nov 2011

Carpi Francesco M, Xu Jialin, Vincenzetti Silvia, Vita Alberto, Cai Wei-Min, Napolioni Valerio

Abstract excerpt

BACKGROUND: The CDA 79A>C (K27Q, rs2072671) functional SNP has recently shown a crucial role in the pharmacogenetics of cytidine-based anticancer drugs widely administered to different subsets of patients. Current gold standard in screening for the CDA rs2072671 is the sequence-based genotyping method. Here we developed a novel, rapid Allele-Specific PCR method for CDA rs2072671 genotyping. METHODS: DNA was...

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Source

Identifiers

PMID: 21884687
DOI: 10.1016/j.cca.2011.08.015

Genes

CDA

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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