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Article

Full-length nucleotide sequences of 30 common SLC44A2 alleles encoding human neutrophil antigen-3.

Transfusion - 1 Mar 2016

Chen Qing, Srivastava Kshitij, Ardinski Stefanie C, Lam Kevin, Huvard Michael J, Schmid Pirmin, Flegel Willy A

Abstract excerpt

BACKGROUND: Human neutrophil antigen-3a (HNA-3a) alloantibodies can cause severe transfusion-related acute lung injury. The frequencies of the single-nucleotide polymorphisms (SNPs) indicative of the two clinically relevant HNA-3a/b antigens are known in many populations. In this study, we determined the full-length nucleotide sequence of common SLC44A2 alleles encoding the choline transporter-like protein-2 that...

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PMID: 26437811
DOI: 10.1111/trf.13300
PMCID: PMC4783217

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