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Article

Using penalised logistic regression to fine map HLA variants for rheumatoid arthritis.

Annals of human genetics - 1 Nov 2011

Vignal Charlotte M, Bansal Aruna T, Balding David J

Abstract excerpt

Rheumatoid arthritis (RA) is strongly associated with the human leukocyte antigen (HLA) genomic region, most notably with a group of HLA-DRB1 alleles termed the shared epitope (SE). There is also substantial evidence of other risk loci in the HLA region, but refinement has been hampered by extensive linkage disequilibrium (LD). Using genotype imputation, we analysed 6575 RA cases and controls with genotypes at...

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Share to Arthritis, Rheumatoid
Share to Case-Control Studies
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Histocompatibility Antigens Class I

Share to HLA-DP beta-Chains

Share to Logistic Models

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 21883133
DOI: 10.1111/j.1469-1809.2011.00670.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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