Article
Fine mapping the TAGAP risk locus in rheumatoid arthritis.
Genes and immunity - 1 Jun 2011
Chen R, Stahl E A, Kurreeman F A S, Gregersen P K, Siminovitch K A, Worthington J, Padyukov L, Raychaudhuri S, Plenge R M
Abstract excerpt
A common allele at the TAGAP gene locus demonstrates a suggestive, but not conclusive association with risk of rheumatoid arthritis (RA). To fine map the locus, we conducted comprehensive imputation of CEU HapMap single-nucleotide polymorphisms (SNPs) in a genome-wide association study (GWAS) of 5,500 RA cases and 22,621 controls (all of European ancestry). After controlling for population stratification with...
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