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Article

Development and characterization of an organotypic model of Barrett's esophagus.

Journal of cellular physiology - 1 Jun 2012

Kosoff Rachelle E, Gardiner Kristin L, Merlo Lauren M F, Pavlov Kirill, Rustgi Anil K, Maley Carlo C

Abstract excerpt

Understanding the molecular and cellular processes underlying the development, maintenance, and progression of Barrett's esophagus (BE) presents an empirical challenge because there are no simple animal models and standard 2D cell culture can distort cellular processes. Here we describe a three-dimensional (3D) cell culture system to study BE. BE cell lines (CP-A, CP-B, CP-C, and CP-D) and esophageal squamous...

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Identifiers

PMID: 21882191
DOI: 10.1002/jcp.23007
PMCID: PMC3352665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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