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Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems

1 Dec 2013

Abstract excerpt

Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), graft-versus-host disease (GVHD), and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are common human gastrointestinal diseases that share inflammation as a key driver for their development. A general outcome resulting from these chronic inflammatory conditions is increased oxidative stress. Oxidative stress is caused by...

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PMID: 24564965
DOI: 10.1186/scrt366

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