Article
Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells.
Gastroenterology - 1 Jun 2007
Milano Francesca, van Baal Jantine W P M, Buttar Navtej S, Rygiel Agnieszka M, de Kort Floor, DeMars Cathrine J, Rosmolen Wilda D, Bergman Jacques J G H M, VAn Marle Jan, Wang Kenneth K, Peppelenbosch Maikel P, Krishnadath Kausilia K
Abstract excerpt
BACKGROUND & AIMS: Barrett's esophagus (BE) is a metaplastic condition in which normal squamous esophageal epithelium is replaced by columnar epithelium. It is proposed that one of the possible mechanisms is dedifferentiation of squamous epithelium into columnar epithelium. The pathophysiology th...
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