Article
New insights into osteoarthritis: early developmental features of an ageing-related disease.
Current opinion in rheumatology - 1 Sept 2008
Bos Steffan Daniël, Slagboom P Eline, Meulenbelt Ingrid
Abstract excerpt
PURPOSE OF REVIEW: This review addresses possible common mechanisms of how recently identified consistent osteoarthritis susceptibility genes influence both the onset of osteoarthritis and its progression towards clinical outcomes. RECENT FINDINGS: Genetic association studies have identified a few consistent osteoarthritis susceptibility genes (FRZB, GDF5, and DIO2) that replicate across different populations....
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