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Article

Hypervariable region 5'-flanking [Leu A3]insulin gene of insulin Tochigi is different from those of insulin Wakayama I,II.

Diabetes research and clinical practice - 1 Mar 1990

Awata T, Iwamoto Y, Matsuda A, Kuzuya T

Abstract excerpt

Three families with abnormal insulinemia have been reported in Japan and sequencing analysis revealed that they had the same point mutation in one allele of the insulin genes causing [Leu A3]insulin. To estimate whether or not this same mutation came from a common ancestor we determined the seque...

Topics

Base Sequence
Genes
Genetic Variation
Humans
Insulin
Japan
Leucine
Molecular Sequence Data
Mutation
Repetitive Sequences, Nucleic Acid
Restriction Mapping

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Identifiers

PMID: 2187661
DOI: 10.1016/0168-8227(90)90115-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2187661-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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