Allelic divergence in the human insulin gene provides evidence for intragenic recombination events in the non-coding regions: evidence for existence of new alleles.

doi:10.1007/BF00283261

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Article

Allelic divergence in the human insulin gene provides evidence for intragenic recombination events in the non-coding regions: evidence for existence of new alleles.

Molecular & general genetics : MGG - 28 Oct 1994

Kim Y S, Kim M H, Choi Y K, Kim C H, Lee D S

Abstract excerpt

Intragenic polymorphism of the human insulin gene (INS) was investigated in Korean subjects. The 1.9 kb INS sequence, including the 5' to 3' flanking regions, was amplified using the polymerase chain reaction (PCR), and analyzed by direct sequencing. All nucleotide sequences in the coding regions...

Topics

Alleles
Base Sequence
DNA
Diabetes Mellitus, Type 2
Genetic Variation
Humans
Insulin
Molecular Sequence Data
Polymerase Chain Reaction
Recombination, Genetic

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