[Study on base insertion/deletion of CAG-rich region in insulin receptor substrate-1 5'-regulatory sequence].

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Article

[Study on base insertion/deletion of CAG-rich region in insulin receptor substrate-1 5'-regulatory sequence].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University - 28 Apr 2001

Huang J J, Song H P

Abstract excerpt

To study the relationship of the polymorphism of the insulin receptor substrate-1 (IRS-1) gene 5'-flanking regulatory sequence and Type 2 diabetes, the IRS-1 gene 5'-flanking regulatory sequence was scanned by PCR-SSCP in 78 healthy control subjects and 76 Type 2 diabetic subjects. Applying PCR-denatured polyacrylamide gel electrophoresis and silver staining, the insertion/deletion polymorphism of the CAG-rich...

Topics

Adult
Alleles
DNA
DNA Transposable Elements
Diabetes Mellitus, Type 2
Female
Humans
Insulin Receptor Substrate Proteins
Male
Middle Aged
Phosphoproteins
Polymorphism, Genetic
Sequence Analysis, DNA
Sequence Deletion

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Open in PubMed

Identifiers

PMID: 12536635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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