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Article

Escherichia coli expression and processing of human interleukin-1 beta fused to signal peptides.

DNA and cell biology - 1 Apr 1990

Curry K A, Yem A W, Deibel M R, Hatzenbuhler N T, Hoogerheide J G, Tomich C S

Abstract excerpt

Escherichia coli expression, processing, and secretion of human interleukin-1 beta (IL-1 beta) fused to the signal peptide of E. coli OmpA or PhoA protein were studied. With fusion to either signal sequence, high-level expression was observed and the products accumulated to about 20% of total cell protein. In the fusion to OmpA leader sequence, more than 50% of the product has the OmpA signal peptide removed...

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Identifiers

PMID: 2187479
DOI: 10.1089/dna.1990.9.167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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