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Article

Effect of OmpA signal peptide mutations on OmpA secretion, synthesis, and assembly.

Journal of bacteriology - 1 Mar 1991

Tanji Y, Gennity J, Pollitt S, Inouye M

Abstract excerpt

In previous investigations, we have examined the effect of OmpA signal peptide mutations on the secretion of the two heterologous proteins TEM beta-lactamase and nuclease A. During these studies, we observed that a given signal peptide mutation could affect differentially the processing of precursor OmpA-nuclease or precursor OmpA-lactamase. This observation led us to further investigate the influence of the...

Topics

Amino Acid Sequence
Bacterial Outer Membrane Proteins
DNA Mutational Analysis
Hot Temperature
Macromolecular Substances
Molecular Sequence Data
Molecular Weight
Mutation
Protein Processing, Post-Translational
Protein Sorting Signals

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Identifiers

PMID: 2002002
DOI: 10.1128/jb.173.6.1997-2005.1991
PMCID: PMC207733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2002002-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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