Article
Artifactual processing of penicillin-binding proteins 7 and 1b by the OmpT protease of Escherichia coli.
Journal of bacteriology - 1 Jan 1994
Henderson T A, Dombrosky P M, Young K D
Abstract excerpt
Penicillin-binding proteins (PBPs) were visualized in strains of Escherichia coli that carried mutations in one or more of the following protease genes: tsp, degP, ptr, and ompT. In the absence of a functional ompT gene, PBPs 1b alpha and 7 were not processed to the shortened forms 1b beta and 8, respectively. Cleavage of PBPs 1b alpha and 7 could be restored by introduction of a plasmid carrying the wild-type...
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