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Article

Ancestral haplotypes: conserved population MHC haplotypes.

Human immunology - 1 Aug 1992

Degli-Esposti M A, Leaver A L, Christiansen F T, Witt C S, Abraham L J, Dawkins R L

Abstract excerpt

We describe here a number of Caucasoid MHC haplotypes that extend from HLA-B to DR and that have been conserved en bloc. These haplotypes and recombinants between any two of them account for 73% of unselected haplotypes in our Caucasoid population. The existence of ancestral haplotypes implies conservation of large chromosomal segments. Irrespective of the mechanisms involved in preservation of ancestral...

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Identifiers

PMID: 1464552
DOI: 10.1016/0198-8859(92)90023-g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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