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Article

Association between tryptophan hydroxylase-2 gene and late-onset depression.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Sept 2011

Pereira Patricia de Araújo, Romano-Silva Marco Aurélio, Bicalho Maria Aparecida Camargos, De Marco Luiz, Correa Humberto, de Campos Simone Becho, de Moraes Edgar Nunes, Torres Karen Cecilia de Lima, de Souza Bruno Rezende, de Miranda Debora Marques

Abstract excerpt

OBJECTIVE: The aim of this study was to examine the association between polymorphisms (SNP) in the tryptophan hydroxylase-2 (TPH2) gene and late-onset depression (LOD) in the Brazilian population. METHODS: We genotyped 8 tag SNPs in the TPH2 gene in 84 outpatients with LOD and 79 individuals belonging to the comparison group to investigate an association between the TPH2 gene and LOD. RESULTS: Our findings...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21873838
DOI: 10.1097/JGP.0b013e31820eeb21

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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