Article
Replication study of chr17q25 with cerebral white matter lesion volume.
Stroke - 1 Nov 2011
Verhaaren Benjamin F J, de Boer Renske, Vernooij Meike W, Rivadeneira Fernando, Uitterlinden André G, Hofman Albert, Krestin Gabriel P, van der Lugt Aad, Niessen Wiro J, Breteler Monique M B, Ikram M Arfan
Abstract excerpt
BACKGROUND AND PURPOSE: Recently, the first genomewide association study on cerebral white matter lesion burden identified chr17q25 to be significantly associated with white matter lesions. We report on the first independent replication study of this genetic association. METHODS: In a population-based cohort study, we investigated the association between the 6 genomewide significant single nucleotide...
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