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Article

Genome-wide scan for white matter hyperintensity: the Framingham Heart Study.

Stroke - 1 Jan 2006

DeStefano Anita L, Atwood Larry D, Massaro Joseph M, Heard-Costa Nancy, Beiser Alexa, Au Rhoda, Wolf Philip A, DeCarli Charles

Abstract excerpt

BACKGROUND AND PURPOSE: White matter hyperintensity (WMH) volume is associated with aging and cerebrovascular disease and has been demonstrated to have a high heritability in the Framingham Heart Study as well as in other studies. We performed a genome-wide linkage analysis to identify chromosomal regions that may harbor genes influencing WMH in a family-based sample of the Framingham Heart Study. METHODS: Brain...

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Identifiers

PMID: 16322484
DOI: 10.1161/01.STR.0000196987.68770.b3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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