Article
Human phenylethanolamine N-methyltransferase genetic polymorphisms and exercise-induced epinephrine release.
Physiological genomics - 13 May 2008
Ji Yuan, Snyder Eric M, Fridley Brooke L, Salavaggione Oreste E, Moon Irene, Batzler Anthony, Yee Vivien C, Schaid Daniel J, Joyner Michael J, Johnson Bruce D, Weinshilboum Richard M
Abstract excerpt
Phenylethanolamine N-methyltransferase (PNMT) catalyzes the synthesis of epinephrine from norepinephrine. We previously identified and functionally characterized common sequence variation in the PNMT gene. In the present study, we set out to determine whether common PNMT genetic polymorphisms might be associated with individual variation in circulating epinephrine levels during exercise in 74 Caucasian American...
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