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Article

Polymorphism of the DNA methyltransferase 1 gene is associated with the susceptibility to essential hypertension in male.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2018

Chen Hui-Ling, Li Zhan-Ming, Liu Jin-Feng, Han Bing, Wu Zhao-Xia, Mao Yu-Qin, Sun Ke-Yu, Wang Li-Shun

Abstract excerpt

Essential hypertension is a leading global public health issue, billions of people suffered from it every year. Recently, multiple evidence suggests that DNA methylation play an important role in regulating blood pressure. Here, we tested the risk for essential hypertension conferred by single nucleotide polymorphisms (SNPs) within DNA methyltransferase 1 (DNMT1). Three loci (rs2228611, rs2228612, and rs16999593)...

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Source

Identifiers

PMID: 29400588
DOI: 10.1080/10641963.2018.1425420

Genes

DNMT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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