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Influence of variation in the follicle-stimulating hormone receptor gene (FSHR) and age at menopause on the development of Alzheimer's disease in women.

Dementia and geriatric cognitive disorders - 1 Jan 2011

Corbo Rosa Maria, Gambina Giuseppe, Broggio Elisabetta, Scacchi Renato

Abstract excerpt

BACKGROUND: The higher prevalence of sporadic Alzheimer's disease (AD) in women may be explained by their longer life expectancy, but also by biological gender-specific factors such as a woman's past fertility. METHODS: We investigated the relationship between fertility and susceptibility to AD in women by studying two polymorphisms at codons 307 and 680 of the follicle-stimulating hormone receptor gene (FSHR)...

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PMID: 21865747
DOI: 10.1159/000330472

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FSHR

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