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Article

The relationship between fertility and lifespan in humans.

Age (Dordrecht, Netherlands) - 1 Dec 2011

Kuningas Maris, Altmäe Signe, Uitterlinden André G, Hofman Albert, van Duijn Cornelia M, Tiemeier Henning

Abstract excerpt

Evolutionary theories of aging predict a trade-off between fertility and lifespan, where increased lifespan comes at the cost of reduced fertility. Support for this prediction has been obtained from various sources. However, which genes underlie this relationship is unknown. To assess it, we first analyzed the association of fertility with age at menarche and menopause, and with mortality in 3,575 married female...

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Source

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Identifiers

PMID: 21222045
DOI: 10.1007/s11357-010-9202-4
PMCID: PMC3220400

Genes

FSHR
FST
INHBA
LHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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