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Article

A polymorphism of apolipoprotein E (APOE) gene is associated with age at natural menopause in Caucasian females.

Maturitas - 20 Jan 2009

He Li-Na, Recker Robert R, Deng Hong-Wen, Dvornyk Volodymyr

Abstract excerpt

OBJECTIVE: The present study aimed to investigate possible association of the apolipoprotein E (APOE) gene polymorphisms with age at natural menopause (ANM) in Caucasian females. DESIGN: Four SNPs (including two replacements, SNP3 Cys112Arg and SNP4 Arg158Cys) were genotyped in 253 randomly selected unrelated Caucasian women having experienced natural menopause. The comprehensive statistical analyses focusing on...

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Source

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Identifiers

PMID: 19058936
DOI: 10.1016/j.maturitas.2008.10.011
PMCID: PMC2734973

Genes

APOE

Provenance

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