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Article

Combined effect of apolipoprotein e genotype and past fertility on age at onset of Alzheimer's disease in women.

Dementia and geriatric cognitive disorders - 1 Jan 2007

Corbo Rosa Maria, Gambina Giuseppe, Ulizzi Laura, Monini Patrizia, Broggio Elisabetta, Rosano Aldo, Scacchi Renato

Abstract excerpt

BACKGROUND: Various risk factors influence the development of Alzheimer's disease (AD). Apolipoprotein E (APOE) e*4 allele has a major role in AD susceptibility and its presence reduces age at AD onset. APOE is also thought to influence human reproduction, and common APOE genotypes seem to be associated with differential fertility. With this study, we investigated possible relationships between APOE genotype,...

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Identifiers

PMID: 17565217
DOI: 10.1159/000103866

Genes

APOE

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