Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease.

Human brain mapping - 15 Dec 2020

de Lange Ann-Marie G, Barth Claudia, Kaufmann Tobias, Maximov Ivan I, van der Meer Dennis, Agartz Ingrid, Westlye Lars T

Abstract excerpt

Sex hormones such as estrogen fluctuate across the female lifespan, with high levels during reproductive years and natural decline during the transition to menopause. Women's exposure to estrogen may influence their heightened risk of Alzheimer's disease (AD) relative to men, but little is known about how it affects normal brain aging. Recent findings from the UK Biobank demonstrate less apparent brain aging in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Factual

Share to Estradiol

Share to Estrogens

Share to Hormone Replacement Therapy

Share to Neuroimaging

Share to Parity

Source

Open in PubMed Open full text

Identifiers

PMID: 32856754
DOI: 10.1002/hbm.25180
PMCID: PMC7670641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease.PMID 32856754Read ↗

Women’s brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer’s diseaseSemantic proximity Read ↗

Reproductive lifespan and hormonal therapy in relation to later-life neurovascular health: A population-based study of women in the Gothenburg H70-1944 Birth CohortSemantic proximity Read ↗

Investigating the synergistic effects of hormone replacement therapy, apolipoprotein E and age on brain health in the UK Biobank.Semantic proximity Read ↗

Female-specific factors are associated with cognition in the UK Biobank cohortSemantic proximity Read ↗

Role of estrogen in women's Alzheimer's disease risk as modified by APOE.Semantic proximity Read ↗

Reproductive history differentially shapes the neural response of middle-aged females to estradiol therapy after a metabolic challengeSemantic proximity Read ↗

Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer’s diseaseSemantic proximity Read ↗

Estrogen activates Alzheimer's disease genesSemantic proximity Read ↗

Age, APOE and sex: Triad of risk of Alzheimer's disease.Semantic proximity Read ↗

Hormone replacement therapy and dementia risk among postmenopausal women: evidence from the UK BiobankSemantic proximity Read ↗

Trajectories and phenotypes with estrogen exposures across the lifespan: What does Goldilocks have to do with it?Semantic proximity Read ↗

Associations of endogenous and exogenous hormonal exposures and cardiovascular disease in women – A FinnGen studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.