Article
Nucleoside reverse transcriptase inhibitor resistance mutations in subtype F1 strains isolated from heavily treated adolescents in Romania.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jan 2009
Paraschiv Simona, Otelea Dan, Baicus Cristian, Tinischi Mihaela, Costache Marieta, Neaga Emil
Abstract excerpt
OBJECTIVE: To examine the nucleoside reverse transcriptase inhibitor (NRTI) resistance mutations in the reverse transcriptase gene of HIV-1 F1 subtype strains isolated from heavily treated adolescents. METHODS: Three hundred and fifty reverse transcriptase (RT) genotypes with at least three NRTI resistance mutations were included in this study; the corresponding strains were isolated from adolescents with a...
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