Article
Variation in complement component C1 inhibitor in age-related macular degeneration.
Immunobiology - 1 Feb 2012
Gibson J, Hakobyan S, Cree A J, Collins A, Harris C L, Ennis S, Morgan B P, Lotery A J
Abstract excerpt
This study assessed variation in plasma levels of the complement regulatorC1 inhibitor (C1inh) in patients with age related macular degeneration (AMD) and controls. Plasma from391 AMD cases and 370 controls was assayed by rate nephelometry to determine C1inh protein levels. Protein levels were analysed for relationships with age, gender, smoking, AMD disease status and genetic variation in the SERPING1 gene,...
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