Article
Determination of a gene and environment risk model for age-related macular degeneration.
The British journal of ophthalmology - 1 Oct 2010
Gibson Jane, Cree Angela, Collins Andrew, Lotery Andrew, Ennis Sarah
Abstract excerpt
BACKGROUND/AIMS: We have recently identified an association between age-related macular degeneration (AMD) and genetic variants in the serpin peptidase inhibitor, clade G, member 1 (SERPING1) gene. In the current study we interrogated the genomic region in linkage disequilibrium (LD) with the SERPING1 gene, and modelled the contribution to disease of known genetic and environmental AMD risk factors. METHODS: We...
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